Katinon
The 2-bromo-product,
the propyl arm is substituted with Br at the 2 position, from reaction with HBr, is in Beilstein on p228 of 19, 3/4, I. This bromo material is reported to have a density between 1.5614 and 1.5640, with the following boiling points for given pressures in mmHg:
C10H11O2Br
mmHg
bp
13 154-157 °C
9 145 °C
5 130-135 °C
References for this 2-bromopropyl product include (from Beilstein)
Orcutt, Bogert, Am. Soc. 58 [1936] 2055;
Liebermann et al, Am. Soc. 69 [1947] 1540;
Sakakibira, J. Chem. Soc Japan Pure Chem. Sect 73, [1952] 235;
C. A. 1953 10511.
Markownikov Br-product
Getting this Markownikov depends on the absence of peroxides in the precursor materials, such peroxides can be sequestered out by the addition of a small quantity of hydroquinone (used in photography) to the reaction. The 2-iodo-equivalent of the above, C10H11O2I is produced with HI under DMSO.
Бромирование.
В приведенных патентах вы увидите как барботирование, так и растворы, так и инситу с ДМСО.
